Inverse vaccines have shown promise treating type I, multiple sclerosis, and some other autoimmune diseases.
‘Inverse vaccines’: the promise of a ‘holy grail’ treatment for autoimmune diseases
“The study looked at celiac disease, in which the immune system attacks the intestinal lining when it detects the presence of gluten, a protein found in wheat and other grains.
Over two weeks, 33 celiac patients who were in remission ingested gluten; about half had received the inverse vaccine beforehand, while the other half got a placebo. After two weeks, researchers examined the subjects’ intestinal lining and found that the inverse vaccine group had no damage, while the placebo group showed a noticeable worsening of symptoms.
The basic idea of inverse vaccines rests on using certain synthetic nanoparticles attached to particular disease-related proteins – called antigens – as targeted messengers to retrain the immune system. The nanoparticles mimic dying human cells, a normal ongoing process. Although these dying cells are “foreign”, the immune system knows not to attack them. The immune system learns to ignore both the nanoparticles and the attached proteins, and stops attacking the body.
In 2023, Hubbell and his colleagues
published a peer-reviewed paper in Nature showing that this method could halt the mouse version of multiple sclerosis (MS), a disease in which the immune system attacks nerve cells in the brain and body. Over the past eight months, Anokion, the company started by Hubbell and others to commercialize their work, has announced successful early trials in humans in both
celiac disease and
MS.”
We can only hope maga doesn’t fuck this up for everyone.
